Epidemiology & Prevention

Chennai, HIV, HCV and Eeral Study (CHHEERS)

YRGCARE PI

Suniti Solomon; Pradeep Amrose

PROJECT SUMMARY

This study characterizes the associations between HIV, Hepatitis C virus (HCV), tuberculosis, alcohol use and liver disease in a population of injection drug users (IDUs) in southern India (Chennai). These data will help to inform future treatment initiatives and interventions to reduce the burden of liver disease in a population with a confluence of hepatotoxic risk factors.

PARTNER INSTITUTIONS

Johns Hopkins Bloomberg School of Public Health, USA; Johns Hopkins University School of Medicine, USA

FUNDING SOURCE

National Institute on Drug Absue, National Institutes of Health, USA

Preventing HIV among wives of men who have sex with men in India

YRGCARE PI

Aylur K Srikrishnan

PROJECT SUMMARY

This mixed-methods epidemiology study seeks to identify interventions to improve HIV testing among female spouses of men who have sex with men in India. This study will also characterize prevalence and correlates of HIV and STIs among spouses of married MSM in three Indian cities.

PARTNER INSTITUTIONS

Johns Hopkins University School of Medicine, USA; Johns Hopkins Bloomberg School of Public Health, USA

FUNDING SOURCE

National Institute of Mental Health, National Institutes of Health, USA; Indian Council of Medical Research, India

PUBLICATIONS

Integrated Care Centers to Improve HIV Outcomes in Vulnerable Indian Populations

YRGCARE PI

Suniti Solomon; Muniratnam Suresh Kumar; Aylur K Srikrishnan

PROJECT SUMMARY

This study evaluates the community-level effectiveness of IDU and MSM-oriented integrated care clinics (ICCs) to improve outcomes among vulnerable Indian populations along the seek, test, treat, and retain continuum

PARTNER INSTITUTIONS

Johns Hopkins University School of Medicine, USA; Johns Hopkins Bloomberg School of Public Health, USA; National AIDS Control Organization, India; National Institute of Allergy and Infectious Diseases, NIH, USA

FUNDING SOURCE

National Institute on Drug Absue, National Institutes of Health, USA; National Institute of Mental Health, National Institutes of Health, USA;

PUBLICATIONS

Solomon SS, Lucas GM, Celentano DD et al. Beyond surveillance: a role for respondent-driven sampling in implementation science. Am J Epidemiol. 2013 Jul 15;178(2):260-7. \Epub 2013 Jun 25. PMID: 23801014;PMCID: PMC37

Solomon SS, Mehta SH, Srikrishnan AK et al. , Solomon S, McFall AM, Laeyendecker O, Celentano DD, Iqbal SH, Anand S, Vasudevan CK, Saravanan S, Lucas GM, Kumar MS, Sulkowski MS, Quinn TC. Burden of hepatitis C virus disease and access to hepatitis C virus service. Lancet Infect Dis. 2015; 15:36-45. PMCID PMC4503257

Lucas GM, Solomon SS, Srikrishnan AK et al. High HIV burden among people who inject drugs in 15 Indian cities. AIDS. 2015 Mar 13;29(5):619-28.

Mehta SH, Lucas GM, Solomon S et al. HIV Care Continuum among men who have sex with men and people who inject drugs in India: Barriers to Successful Engagement in Care. Clin Infect Dis. 2015; 61:1732-1741. PMCID:PMC4643485

Solomon SS, Mehta SH, Srikrishnan AK et al. High HIV prevalence and incidence among men who have sex with men (MSM) across 12 cities in

Tomori C, McFall AM, Srikrishnan AK et al. Diverse Rates of Depression Among Men Who Have Sex with Men (MSM) Across India: Insights from a Multi-site Mixed Method Study. AIDS Behav. 2016; 20:304-16

Substance Use Is a Major Barrier to Viral Suppression Among Key Populations in India. Presented at CROI 2016 (manuscript in development):

Respondent-Driven Sampling: An Epidemiological Tool With Interventional Potential. Presented at CROI 2016 (manuscript in development):

Gender-Specific Factors Related to HIV Risks Among People Who Inject Drugs in India. Presented at CROI 2016 (manuscript in development): http://www.croiconference.org/sessions/gender-specific-factors-related-hiv-risks-among-people-who-inject-drugs-india

Directly Observed Therapy for the Delivery of HCV Therapy among HCV-infected individuals in Chennai, India: (The C-DOT Study)

YRGCARE PI

Suniti Solomon; Pradeep Amrose

PROJECT SUMMARY

This non-blinded randomized clinical trial is being conducted to compare treatment completion rates among persons receiving sofosbuvir (SOF) + ribavirin (RBV) with or without pegylated interferon alfa-2a (PEG) using a modified directly observed therapy (mDOT) strategy

PARTNER INSTITUTIONS

"Johns Hopkins University School of Medicine, USA; Johns Hopkins Bloomberg School of Public Health, USA"

FUNDING SOURCE

Intramural YRGCARE

PUBLICATIONS